25 comments

  • elijah aywago

    thank you for this amazing lecture

  • Angelica M Lemos

    i’m taking patho right now for nursing school and my professor is very
    good, but you and your videos are the best !!!!

    Thank you so much for sharing your knowledge 

  • SilverInches890

    Ahh, I LOVE YOU AND THIS VIDEO!

  • Isheoluwa Deshie

    Great video!!! Highly recommended along with his other videos to medics. 

  • Raveendran CP Eradi

    Great work indeed. Thanks for sharing. Need of the hour as diabetis is
    increasing like anything now in India.

  • patil seema

    Very clearly explained on how compications occur and what goes on..
    SUPERRRRRRRRRRRRRR

  • pariya shirali

    Ketones not usually produced in HHS please Explain why?

  • daun binahong cara menghilangkan jerawat

    good information, may I embed this video to my blog?

  • Faten Bin Dayel

    I watch video about pathophysiology of Diabetes Mellitus.
    Pathophysiology of Diabetes Mellitus
    The author is talking about types of diabetes mellitus which are type 1
    when the beta cells in pancreas are completely destroyed by virus (immune
    disease) so, there is loss of insulin production and the second is type
    2 which is inulin resistance and its occur when there is dysfunction in
    cells not in beta cells of pancreas and this is occur because of high level
    triglyceride (fat) in the circulation so, the glucose is high in the blood
    so, high insulin production and then after years it burns out and diabetes
    occur.

    The author is talking about one of diabetes complication which is Diabetes
    Ketoacidosis (DKA) and its occurs when the glucose increase and the
    insulin decrease and this occur if there is infection or the patient dos
    not take the insulin so, the cells use the proteins and fats to produce he
    energy instead of glucose which then produce dangerous end product and very
    harmful for the body.

    the last thing the author is talking about long term effect of
    Diabetes Millets if it is not control. the hyperglycemia cause inflammation
    which affect the heart, eyes,kidnyes and arteries.

    in my opinion, the diabetic patient should control his or her blood glucose
    by take the medication every day and do exercise in order to control the
    blood glucose. Also, he or she should make regular diet with low sugar and
    carbohydrate. 

  • Belinda Gomez

    Finally Its clear! Thank you

  • jamie coughlin

    Hi Dr. Wolf, These videos are so helpful!
    I am trying to get ready for my final in Patho and can’t figure out what
    pathway is activated in the kidneys to increase urine and excrete the
    additional serum K+ during DKA? Is it the RAAS?
    Thank you!

  • Edward Pinder

    Hi thanks a lot. Can I ask are the neurological complications eg sensory
    loss in the feet die to reduce BS to nerves and they die? Thanks

  • Inder Singh

    Where is the next lecture after this?

  • rmcdaniel423

    Excellent tutorial, as always.
    Now, what I REALLY need is a tutorial on how to motivate my middle aged
    patients to eat a healthy diet, exercise daily, quit smoking, pursue
    fulfilling hobbies, engage in meaningful relationships, get quality sleep,
    and take their damn meds as directed. The first person to cure the problem
    of patient compliance will win a Nobel prize and be showered with so much
    money that the accountants will have to learn scientific notation just to
    keep track of it all.

  • SeekTruthinLight

    And there is poorly understood conditions,even poorly addressed underlying
    systemic fungal infections which hijack the immune systems producing
    plaques that block and gum up the body and its structures; the skin,
    organs and liver, in part, producing an inflammatory reaction the body
    tries to fix. Many fungus grow undetected or unrecognized, growing under
    the skin, masked by the color of the blood and the inflammation process
    using the fatty acids, causing obesity in part, in the infection trying to
    hide and protect itself. These fungal conditions are often seen as part of
    the body, being responsible for tough feet and rugged hands and face,
    seen as we get older. Its progressive attacks in its way, produces signs,
    of symmetrical patterns in the skin and are like unto five leaf daisy’s,
    where out of its center it reproduces, producing the red fluid being in
    part blood mixed with its part, having a histamine response, producing
    inflammation and mild burning, causing an itch as it multiplies. It later
    causes many symptoms collectively, including burning painful feet and
    hands, head ache, effecting the eyes, sneezing and a light pinkish velvety
    rash. It’s symptoms are vague and mild at first, seeming like allergies,
    producing little fever, clogging up the micro vessels and tissue
    with whitish yellow fatty plaque in the tissue as it forms, which goes
    through out the body system, even in the heart and the arteries, being an
    inflammatory agent in the body. It is largely untreated systemically unless
    it is symptomatic addressed by doctors who are in the spirit to recognize
    it, in truth; It is seen in immune compromised and the poor, treating its
    symptoms, in part, topically, like skin out breaks, often labeled as other
    conditions; where fear and doubt hinders treatment because of cost, or it
    being unrecognized, even by policy, because of fear and dangers of treating
    with antifungals later, when it has clogged the liver. Its seems to be in
    the order of the structures of histoplasmosis or related strains.
    Ironically it’s patterns appears to be the fungus that grows on Peaches,
    where its flower like patterns and the way it reproduces from the center of
    it, is seen. It continues to grow as a chain, forming larger circular
    patterns growing on the underside of the skin, not on top like that of ring
    worm or other topical fungal infections. It is masked by inflammation and
    the subtle swelling hiding it, as to be largely unrecognized as a threat,
    where many live their lives without many symptoms, in it being common, save
    those who appear to be more susceptible in certain strains, with the diet
    being a factor. It mimics many other conditions, even mosquito bites in it
    way of being, and even having the appearance of the red line of
    sepsis as the fluid released in propagation subtly erodes its way through
    the skin structures to then fade as bite like bumps appear along the line,
    as a new flower like clusters grow, in the itching of the immune response.
    So it hides producing little symptoms, until it flares up, following in
    part the outer surfaces of veins and arteries. It causes headaches, in that
    of the skin and the internal skin like structures of the head. When exposed
    to spores of another, its sexual counterpart, like in peach season, it
    blooms to begin reproducing, causing annoying allergy symptoms in its
    subtly, where we treat it as allergies. It is responsible for many of the
    symptoms and conditions as we age, leaving its mark of thinness skin
    in older people. It later effects the gut in irritable bowl and in other
    organs with its mild vague pain at first, even worse in that of a more
    virulent strains. In part, it blocks vessels and arteries in part,
    redirecting circulation for its own purpose, where the sticky plaque
    prevents the full vascularization process causing lack of hair growth,
    subtly effecting the lungs, causing tiredness and yarning. For me it has
    took its toll, being well formed and deeply rooted, clogging my liver and
    body with plaque and inflammation, having had caused meningitis headache,
    and the out break of the rash, 3 months before; where I saw
    the flowerlike circular patterns on the skin and beard, recognizing
    the scaring in gray hair, in treatment. I am responding well, in the
    headaches having gone away and most of the burning sensation, even in hair
    regrowth on the arms and legs as the swelling and plaque has gone away,
    even the pitting edema in my legs, the redness and swelling in the feet and
    ankles, the red beer drinkers rash have gone for the most part, after 1
    month of treatment, save the few areas more deeply rooted, remaining under
    the skin in palms the and soles of the feet still producing the red burning
    fluid, in part. It was thought I had diabetes because of the swelling and
    redness and burning in my feet, but levels were within normal limits. The
    Gaul bladder was clogged and so removed, with the liver being clogged and
    swollen and has since has returned to normal size and function with
    antifungal treatment. I lost about 20 pounds in a months, as the swelling
    and edema has gone, where it, being all over the body in its subtly,
    appeared to be fat, but in truth was that of process of the underlying
    condition, healing in the removal of that which gummed up the
    body, producing a very sticky gummy stool at first, being that of the
    remains of the plaque, produced in error, made up of fatty acids and that
    of complex molecules of corn syrup, carbohydrates and food components, and
    the fungal parts being of plant like components in the processes of DNA, in
    its merging with that of another, that of the host, of its structures,
    being of the elements of the human body, all of which comes from the
    elements of the earth. So it is one of those things being mistaken or
    unrecognized, difficult to pinpoint, which affects some more than
    others, in that of the way of the world. And like that of the unseen
    “spirits of being” of the world, not being addressed, going unnoticed in
    part, in the lack of understanding of our ways, like that of fear, doubt
    and pride, in its effect, hindering us from benefitting of the way of
    truth. In our recognizing the truth of our errors of spirit, we
    see error causes suffering and death and lack of prosperity and health,
    even as that which is hidden or unaddressed rises to humble us in the truth
    of our error, seen in the acts of denial in terrorism, or in error
    suffering in austerity, poverty and hunger because of the error of the
    spirits of man; where its seen in that of those who respond to our spirits
    of denial and error, later humbled to the truth in sacrificing and
    suffering in war afterwards in the loss. And so we suffer in the ways of
    the world, both spiritually and physically, in part, in the truth going
    unrecognized as to the way of preserving life in love, because of the
    spirits of fear, doubt and pride, in not going the way of love, seen in
    Jesus. Wow!

  • bianca10290

    this might be a dumb question, but what are bg’s?

  • swcoast

    I’ll take the survey if you are still in need of participants – the pop-up
    at the end of the video does not open a URL for some reason.

  • Gem Monika Yamon

    excellent!

  • Guck Foogle

    Apparently, animation is too difficult for pharmacy school professors.
    Wish you would have taught our class! Diabetes does not have to be so
    difficult.

  • GleamEyes

    I was 8 when i got diabetes type 1 i am now 12 sometimes i have a really
    hard time living with i but it allways goes fine :)

  • nicibdanza

    Just wanted to say I love these videos, they are so helpful to me as I go
    through nursing school!

  • Anja Tiller

    Thank you, 

  • Conrad Lopez

    Mr. Wolf great lecture and explanation for the DM.. Plus the expected
    outcomes of both are an added bonus!! Cellular K and serum differences are
    awesome!!
    Thank you

  • cuong vu duc

    Excellent, thank you…

  • Waseem Haddad

    nice lecture, easy to understand, thank you

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